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Ju Huang

Researcher at University of Toronto

Publications -  19
Citations -  7009

Ju Huang is an academic researcher from University of Toronto. The author has contributed to research in topics: Autophagy & Lysosome. The author has an hindex of 15, co-authored 16 publications receiving 5861 citations. Previous affiliations of Ju Huang include University of Michigan & Life Sciences Institute.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Activation of antibacterial autophagy by NADPH oxidases

Ju Huang, +8 more
- 14 Apr 2009 - 
TL;DR: It is found that NOX2-generated ROS are necessary for LC3 recruitment to phagosomes, and a general role for members of the NOX family in regulating autophagy is suggested.
Journal ArticleDOI

Bacteria–autophagy interplay: a battle for survival

Ju Huang, +1 more
- 01 Feb 2014 - 
TL;DR: In this article, the authors discuss canonical and non-canonical autophagy pathways and their current knowledge of antibacterial auto-pathway, with a focus on the interplay between bacterial factors and autophag components.
Journal ArticleDOI

Autophagy and human disease.

Ju Huang, +1 more
- 01 Aug 2007 - 
TL;DR: A fundamental paradox of autophagy is that it can act to promote both cell survival and cell death, depending on the specific conditions, and acts as a mechanism for tumor suppression, although some cancer cells use it as a cytoprotective mechanism.
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Atg22 Recycles Amino Acids to Link the Degradative and Recycling Functions of Autophagy

Zhifen Yang, +4 more
- 01 Dec 2006 - 
TL;DR: A "recycling" model that includes the efflux of macromolecules from the lysosome/vacuole as the final step of autophagy is proposed, which allows the maintenance of protein synthesis and viability during nitrogen starvation.