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Roza Kucharczyk

Researcher at Polish Academy of Sciences

Publications -  58
Citations -  5776

Roza Kucharczyk is an academic researcher from Polish Academy of Sciences. The author has contributed to research in topics: ATP synthase & Mitochondrion. The author has an hindex of 20, co-authored 45 publications receiving 4549 citations. Previous affiliations of Roza Kucharczyk include Centre national de la recherche scientifique & University of Bordeaux.

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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Protein AMPylation by an Evolutionarily Conserved Pseudokinase.

Anju Sreelatha, +16 more
- 18 Oct 2018 - 
TL;DR: It is shown that the highly conserved pseudokinase selenoprotein-O (SelO) transfers AMP from ATP to Ser, Thr, and Tyr residues on protein substrates (AMPylation), uncovering a previously unrecognized activity for a member of the protein kinase superfamily.
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Yeast as a system for modeling mitochondrial disease mechanisms and discovering therapies

Jean-Paul Lasserre, +17 more
- 01 Jun 2015 - 
TL;DR: The use of budding yeast to understand mitochondrial diseases and help in the search for their treatments is discussed, including genetic and chemical screens using yeast.
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Mitochondrial ATP synthase disorders : Molecular mechanisms and the quest for curative therapeutic approaches

Roza Kucharczyk, +7 more
- 01 Jan 2009 - 
TL;DR: The application of novel scientific approaches promises to deepen the understanding of the molecular mechanisms of the ATP synthase, unravel novel therapeutic pathways and improve the unfortunate situation of the patients suffering from such diseases.
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A yeast-based assay identifies drugs active against human mitochondrial disorders

Elodie Couplan, +12 more
- 19 Jul 2011 - 
TL;DR: A rapid, yeast-based assay to screen for drugs active against human inherited mitochondrial diseases affecting ATP synthase, in particular NARP (neuropathy, ataxia, and retinitis pigmentosa) syndrome is established and it is suggested that this type of method could be applied to other mitochondrial diseases.