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Melinda A. Lynch-Day

Researcher at University of Michigan

Publications -  9
Citations -  5592

Melinda A. Lynch-Day is an academic researcher from University of Michigan. The author has contributed to research in topics: Autophagy & BAG3. The author has an hindex of 7, co-authored 9 publications receiving 4514 citations. Previous affiliations of Melinda A. Lynch-Day include Life Sciences Institute.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

The Role of Autophagy in Parkinson’s Disease

Melinda A. Lynch-Day, +4 more
- 01 Apr 2012 - 
TL;DR: The concept and physiological function of autophagy, and the proteins related to autosomal dominant and autosomal recessive PD, particularly α-synuclein and PINK1-PARKIN, as they pertain to autophileagy are introduced.
Journal ArticleDOI

The Cvt pathway as a model for selective autophagy

Melinda A. Lynch-Day, +1 more
- 02 Apr 2010 - 
TL;DR: The Cvt pathway is responsible for the delivery of the hydrolase aminopeptidase I to the vacuole and is the only known biosynthetic pathway that utilizes the core machinery of autophagy.
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The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy

Jens Füllgrabe, +9 more
- 22 Aug 2013 - 
TL;DR: It is reported that induction of autophagy is coupled to reduction of histone H4 lysine 16 acetylation through downregulation of the histone acetyltransferase hMOF (also called KAT8 or MYST1), and it is demonstrated that this histone modification regulates the outcome of Autophagy.
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A Genomic Screen for Yeast Mutants Defective in Selective Mitochondria Autophagy

Tomotake Kanki, +10 more
- 15 Nov 2009 - 
TL;DR: A genome-wide yeast mutant screen forMitophagy-defective strains identified 32 mutants with a block in mitophagy, in addition to the known autophagic-related (ATG) gene mutants, and characterized one of these mutants, ylr356wDelta that corresponds to a gene whose function has not been identified.