Saburo Matsuo

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Results showed that ATF4 is the key signal for autophagy induced by ER-stress, and that Autophagy is switched to apoptosis by subsequent CHOP upregulation, suggesting that the changeover switch between autophagic and apoptosis is located between ATF4 to CHOP in the PERK pathway.

TL;DR: Findings indicate that rER-stress by intracisternal granule accumulation lead to autophagy in exocrine pancreas cells without UPR, suggesting that signal process of Autophagy differs from that of UPR-apoptosis.

TL;DR: Immunohistochemistry for protein gene product 9.5 demonstrated that the loss of genes for trkA, trkB and trkC caused the absence of the immunoreactive innervation of Merkel cells.

TL;DR: The results suggest that the ossification of chondrophytes occurred in parallel with the increase in CGRP-positive fiber density in the synovium during the acute phase of collagenase-induced OA.