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Vivek K. Unni

Researcher at Oregon Health & Science University

Publications -  28
Citations -  6241

Vivek K. Unni is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Alpha-synuclein & Dementia with Lewy bodies. The author has an hindex of 14, co-authored 22 publications receiving 5026 citations. Previous affiliations of Vivek K. Unni include Columbia University & Howard Hughes Medical Institute.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Distinct roles in vivo for the Ubiquitin-Proteasome system and the Autophagy-Lysosomal Pathway in the Degradation of α-Synuclein

Darius Ebrahimi-Fakhari, +7 more
- 12 Oct 2011 - 
TL;DR: A novel link between the UPS, the ALP, and α-synuclein pathology is provided and may have important implications for future therapeutics targeting degradation pathways.
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Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I.

Roger Janz, +6 more
- 01 Nov 1999 - 
TL;DR: The data show that synaptogyrin I and synaptophysin I perform redundant and essential functions in synaptic plasticity without being required for neurotransmitter release itself.
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Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export

Andrea Legati, +41 more
- 27 May 2015 - 
TL;DR: This work has identified in multiple families with PFBC mutations in XPR1, a gene encoding a retroviral receptor with phosphate export function that alters phosphate export, implicating X PR1 and phosphate homeostasis in PFBC.
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Progressive Aggregation of Alpha-Synuclein and Selective Degeneration of Lewy Inclusion-Bearing Neurons in a Mouse Model of Parkinsonism

Valerie R. Osterberg, +5 more
- 03 Mar 2015 - 
TL;DR: It is shown that intracerebral injection of preformed fibrils of recombinant alpha-synuclein can seed aggregation of transgenically-expressed and endogenous alpha- Synuclein in neurons and that seeding may be a pathologically relevant mechanism of progressive neurodegeneration in many synucleinopathies.