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Pu Xia

Researcher at Fudan University

Publications -  66
Citations -  11250

Pu Xia is an academic researcher from Fudan University. The author has contributed to research in topics: Sphingosine kinase & Sphingosine. The author has an hindex of 36, co-authored 64 publications receiving 9892 citations. Previous affiliations of Pu Xia include Harvard University & University of Adelaide.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth.

Pu Xia, +9 more
- 01 Nov 1996 - 
TL;DR: VEGF appears to mediate its mitogenic effects partly through the activation of the PLCgamma and PKC pathway, involving predominately PKC-beta isoform activation in endothelial cells.
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Activation of sphingosine kinase 1 by ERK1/2‐mediated phosphorylation

Stuart M. Pitson, +6 more
- 15 Oct 2003 - 
TL;DR: It is shown that phosphorylation of sphingosine kinase 1 at Ser225 results not only in an increase in enzyme activity, but is also necessary for translocation of the enzyme from the cytosol to the plasma membrane.
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Characterization of the mechanism for the chronic activation of diacylglycerol-protein kinase C pathway in diabetes and hypergalactosemia.

Pu Xia, +5 more
- 01 Sep 1994 - 
TL;DR: Findings have clearly demonstrated a possible common biochemical mechanism by which hyperglycemia and hypergalactosemia can chronically activate the DAG-PKC pathway in the vasculature and could be a possible explanation for the development of diabetic vascular complications.
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An oncogenic role of sphingosine kinase

Pu Xia, +7 more
- 01 Nov 2000 - 
TL;DR: It is found that SphK activity is involved in oncogenic H-Ras-mediated transformation, suggesting a novel signalling pathway for Ras activation and pointing to a new signalling pathway in transformation.