Claus Kerkhoff

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: An ever‐increasing body of information suggests that S 100A9 plays a prominent role in leukocyte trafficking and arachidonic acid metabolism, and elevated levels of S100A9 and S100 a8 in body fluids of inflamed tissues strengthen the view that these molecules are important players in fighting inflammation.

TL;DR: The data indicate that S100A8/A9‐promoted cell growth occurs through RAGE signaling and activation of NF‐κB, which is mediated via RAGE ligation.

TL;DR: It is hypothesized that MRP8 and MRP14 play an important role in leukocyte trafficking, but do not affect neutrophil effector functions.

TL;DR: S100A8/A9 plays an important role in phagocyte NADPH oxidase activation as demonstrated by the impaired oxidase activity in neutrophil‐like NB4 cells, after specific blockage of S100A9 expression, and bone marrow polymorphonuclear neutrophils from S 100A9−/− mice.