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Elizabeth P. Henske

Researcher at Brigham and Women's Hospital

Publications -  232
Citations -  28819

Elizabeth P. Henske is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Tuberous sclerosis & TSC1. The author has an hindex of 65, co-authored 214 publications receiving 24850 citations. Previous affiliations of Elizabeth P. Henske include Cardiff University & University of Texas MD Anderson Cancer Center.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34

Marjon van Slegtenhorst, +40 more
- 08 Aug 1997 - 
TL;DR: Thirty-two distinct mutations were identified in TSC1, 30 of which were truncating, and a single mutation was seen in six apparently unrelated patients, which suggests that hamartin acts as a tumor suppressor.
Journal ArticleDOI

The tuberous sclerosis complex.

Peter B. Crino, +2 more
- 28 Sep 2006 - 
TL;DR: From the Department of Neurology (P.P.N., K.L.C.) and the Division of Medical Genetics (K.B.H.) — both in Philadelphia.
Journal ArticleDOI

HEF1-Dependent Aurora A Activation Induces Disassembly of the Primary Cilium

Elena N. Pugacheva, +4 more
- 29 Jun 2007 - 
TL;DR: It is shown that interactions between the prometastatic scaffolding protein HEF1/Cas-L/NEDD9 and the oncogenic Aurora A kinase at the basal body of cilia causes phosphorylation and activation of HDAC6, a tubulin deacetylase, promoting ciliary disassembly, and that this pathway is both necessary and sufficient for ciliary resorption.