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Philippe Gual

Researcher at French Institute of Health and Medical Research

Publications -  116
Citations -  12363

Philippe Gual is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Fatty liver & Adipose tissue. The author has an hindex of 41, co-authored 107 publications receiving 10383 citations. Previous affiliations of Philippe Gual include Centre national de la recherche scientifique & University of Nice Sophia Antipolis.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Positive and negative regulation of insulin signaling through IRS-1 phosphorylation

Philippe Gual, +2 more
- 01 Jan 2005 - 
TL;DR: This review will provide insight on the current understanding of the regulation of insulin signaling in both physiological and pathological conditions through modulations that occur with regards to the functions of the insulin receptor substrate 1 (IRS1).
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Increased Adipose Tissue Expression of Hepcidin in Severe Obesity Is Independent From Diabetes and NASH

Soumeya Bekri, +17 more
- 01 Sep 2006 - 
TL;DR: Hencidin is a proinflammatory adipokine and may play an important role in hypoferremia of inflammation in obese condition and be a negative regulator of intestinal iron absorption and macrophage iron efflux.
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M2 Kupffer cells promote M1 Kupffer cell apoptosis: a protective mechanism against alcoholic and nonalcoholic fatty liver disease.

Jinghong Wan, +11 more
- 01 Jan 2014 - 
TL;DR: It is suggested that promoting M2‐induced M1 KC apoptosis might prove a relevant strategy to limit alcohol‐ and high fat‐induced inflammation and hepatocyte injury.
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C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet

Marjorie Poggi, +11 more
- 11 Apr 2007 - 
TL;DR: TLR4 influences white adipose tissue inflammation and insulin sensitivity, as well as liver fat storage, and is important in the regulation of metabolic phenotype during a fat-enriched diet.