Gérard Pierron

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: It is uncovered how P-bodies, by condensing and segregating repressed mRNAs, provide a physical substrate for the coordinated regulation of posttranscriptional mRNA regulons.

TL;DR: Paraspeckles are subnuclear structures formed around NEAT1 lncRNA that affect the transcription of several genes, arguing for a novel role for lnc RNA in gene regulation.

TL;DR: Results indicate that micron nuclei can be subjected to autophagic degradation and it can be speculated that removal of micronuclei may contribute to the genome-stabilizing effects of autophagy.

TL;DR: The versatile scaffold ArtiG is employed to generate concentration-dependent RNA–protein condensates within living cells, as a bottom-up approach to study the impact of co-segregated endogenous components on phase separation and shows the role of intracellular RNA in nucleation and sizing of the phase separated Condensates.