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Diane E. Merry

Researcher at Thomas Jefferson University

Publications -  62
Citations -  9010

Diane E. Merry is an academic researcher from Thomas Jefferson University. The author has contributed to research in topics: Spinal and bulbar muscular atrophy & Androgen receptor. The author has an hindex of 32, co-authored 57 publications receiving 7910 citations. Previous affiliations of Diane E. Merry include University of Pennsylvania.

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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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CREB-binding protein sequestration by expanded polyglutamine

TL;DR: Evidence is presented that CREB-binding protein (CBP), a transcriptional co-activator that orchestrates nuclear response to a variety of cell signaling cascades, is incorporated into nuclear inclusions formed by polyglutamine-containing proteins in cultured cells, transgenic mice and tissue from patients with SBMA.
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Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy

TL;DR: In the motor neurons of SBMA patients, there were AR‐immunoreactive ubiquitinated nuclear inclusions that were detected by antibodies that recognize a small portion of the N terminus of the AR protein.
Journal ArticleDOI

Molecular chaperones enhance the degradation of expanded polyglutamine repeat androgen receptor in a cellular model of spinal and bulbar muscular atrophy

TL;DR: It is demonstrated that Hsp70 and its co-chaperone Hsp40 not only increase expanded repeat AR solubility, but function to enhance the degradation of expandedrepeat AR through the proteasome.