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Howard S. Fox

Researcher at University of Nebraska Medical Center

Publications -  252
Citations -  15337

Howard S. Fox is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: Simian immunodeficiency virus & Virus. The author has an hindex of 57, co-authored 237 publications receiving 13235 citations. Previous affiliations of Howard S. Fox include Cold Spring Harbor Laboratory & Scripps Research Institute.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Detection and Typing of Human Papillomavirus in Archival Cervical Cancer Specimens by DNA Amplification With Consensus Primers

TL;DR: A polymerase chain reaction DNA amplification system using two distinct consensus oligonucleotide primer sets for the improved detection and typing of a broad spectrum of human genital papillomavirus (HPV) sequences, including those of novel viruses.
Journal Article

Estrogen regulates the IFN-gamma promoter.

TL;DR: Evidence is reported that expression of the IFN-gamma gene may be subject to direct hormonal control, which may account in part for the ability of estrogen to potentiate many types of immune responses, and for the disproportionate susceptibility of females to autoimmune disease.
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A central role for CD4(+) T cells and RANTES in virus-induced central nervous system inflammation and demyelination.

TL;DR: Data indicate that CD4+ T cells have a pivotal role in accelerating CNS inflammation and demyelination within infected mice, possibly by regulating RANTES expression, which in turn coordinates the trafficking of macrophages into the CNS, leading to myelin destruction.
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Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA.

TL;DR: A global analysis of the whole-blood DNA methylomes of 137 HIV+ individuals under sustained therapy along with 44 matched HIV- individuals finds that decreased HLA methylation is predictive of lower CD4 / CD8 T cell ratio, linking molecular aging, epigenetic regulation, and disease progression.