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Marc Fransen

Researcher at Katholieke Universiteit Leuven

Publications -  105
Citations -  10664

Marc Fransen is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Peroxisome & Peroxisomal targeting signal. The author has an hindex of 42, co-authored 97 publications receiving 8992 citations. Previous affiliations of Marc Fransen include Catholic University of Leuven & University of California, San Diego.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Peroxisomes are signaling platforms for antiviral innate immunity

TL;DR: It is reported that the RIG-I-like receptor (RLR) adaptor protein MAVS is located on peroxisomes and mitochondria and it is found thatperoxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state.
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Role of peroxisomes in ROS/RNS-metabolism: implications for human disease.

TL;DR: Evidence supporting the notion that peroxisomal metabolism and oxidative stress are intimately interconnected and associated with age-related diseases is discussed.
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A mouse model for Zellweger syndrome.

TL;DR: Analysis of the neocortex revealed impaired neuronal migration and maturation and extensive apoptotic death of neurons in the cerebro-hepato-renal syndrome of Zellweger mice.
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The Peroxisome-Mitochondria Connection: How and Why?

TL;DR: A comprehensive look at how peroxisomal and mitochondrial abundance are controlled by common sets of cis- and trans-acting factors and how these organelles cooperate in various metabolic and signaling pathways is provided.