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Tsung Hsien Chuang

Researcher at National Health Research Institutes

Publications -  14
Citations -  4860

Tsung Hsien Chuang is an academic researcher from National Health Research Institutes. The author has contributed to research in topics: Toll-like receptor & Inflammation. The author has an hindex of 10, co-authored 14 publications receiving 3822 citations. Previous affiliations of Tsung Hsien Chuang include China Medical University (Taiwan) & Kaohsiung Medical University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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MicroRNA-19a-3p inhibits breast cancer progression and metastasis by inducing macrophage polarization through downregulated expression of Fra-1 proto-oncogene.

Jingzhen Yang, +10 more
- 05 Jun 2014 - 
TL;DR: Findings indicate that miR-19a-3p is capable of downregulating the M2 phenotype in M2 macrophages and that the low expression of this miRNA has an important role in the upregulation of Fra-1 expression and induction of M2macrophage polarization.
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Toll-like receptor 9 and 21 have different ligand recognition profiles and cooperatively mediate activity of CpG-oligodeoxynucleotides in zebrafish

Da Wei Yeh, +9 more
- 17 Dec 2013 - 
TL;DR: The molecular basis for the activities of CpG-ODN in fish is addressed and the biological functions of fish TLR9 and TLR21 are investigated, suggesting that zebTLR 9 and zEBTLR21 cooperatively mediate the antimicrobial activities of GTCGTT and GACGTT in fish.
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Natural Modulators of Endosomal Toll-Like Receptor-Mediated Psoriatic Skin Inflammation.

Chao-Yang Lai, +5 more
- 13 Aug 2017 - 
TL;DR: Several immune modulatory oligonucleotides and small molecular weight compounds that block the interaction between endosomal TLRs and their ligands are under clinical investigation for their effectiveness in the treatment of psoriasis and might lead to the development of new treatment options.
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USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation

Chih-Hao Lu, +9 more
- 23 Jul 2018 - 
TL;DR: It is suggested that USP17 drives a positive-feedback interaction between macrophages and cancer cells to enhance inflammation and stemness in cancer cells, and promotes lung cancer growth.