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Stephen J. Doxsey

Researcher at University of Massachusetts Medical School

Publications -  114
Citations -  15806

Stephen J. Doxsey is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Centrosome & Microtubule. The author has an hindex of 56, co-authored 114 publications receiving 14392 citations. Previous affiliations of Stephen J. Doxsey include University of Utah & Yale University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal Article

Centrosome Defects and Genetic Instability in Malignant Tumors

TL;DR: Centrosomes in nearly all tumors and tumor-derived cell lines were atypical in shape, size, and composition and were often present in multiple copies, suggesting they may contribute to genetic instability in cancer.
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Pericentrin, a highly conserved centrosome protein involved in microtubule organization

TL;DR: The results suggest that pericentrin is a conserved integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays.
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Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosome.

TL;DR: It is indicated that pericentrin and γ-tubulin assemble into a unique centrosome lattice that represents the higher-order organization of microtubule nucleating sites at the centrosomes.
Journal ArticleDOI

Centriolin Anchoring of Exocyst and SNARE Complexes at the Midbody Is Required for Secretory-Vesicle-Mediated Abscission

TL;DR: It is proposed that centriolin anchors protein complexes required for vesicle targeting and fusion and integrates membrane-vesicle fusion with abscission.