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Pradipta Ghosh

Researcher at University of California, San Diego

Publications -  187
Citations -  10212

Pradipta Ghosh is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Heterotrimeric G protein & Medicine. The author has an hindex of 39, co-authored 155 publications receiving 8115 citations. Previous affiliations of Pradipta Ghosh include Veterans Health Administration & University of California, Los Angeles.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Mannose 6-phosphate receptors: new twists in the tale

TL;DR: Evidence is emerging that one of the M6P receptors can regulate cell growth and motility, and that it functions as a tumour suppressor.
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Cooperation of GGAs and AP-1 in packaging MPRs at the trans-Golgi network

TL;DR: The Golgi-localized, γ-ear–containing, adenosine diphosphate ribosylation factor–binding proteins (GGAs) and the coat protein adaptor protein–1 (AP-1) were shown to colocalize in clathrin-coated buds of the trans-Golgi networks of mouse L cells and human HeLa cells.
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GIV is a nonreceptor GEF for Gαi with a unique motif that regulates Akt signaling

TL;DR: The novel regulatory motif described here provides the structural and biochemical basis for the prometastatic features of GIV, making the functional disruption of this unique Gαi-GIV interface a promising target for therapy against cancer metastasis.
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Sequential interactions with Sec23 control the direction of vesicle traffic

TL;DR: It is demonstrated that an ER-derived vesicle retains its coat until it reaches the Golgi and that Sec23p interacts in a sequential manner with different binding partners, including TRAPPI and Hrr25p, to ensure the directionality of ER–Golgi traffic and prevent the back-fusion of a COPII vesicles with the ER.