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Fiona M. Menzies

Researcher at University of Cambridge

Publications -  51
Citations -  16162

Fiona M. Menzies is an academic researcher from University of Cambridge. The author has contributed to research in topics: Autophagy & Autophagosome. The author has an hindex of 42, co-authored 51 publications receiving 13660 citations. Previous affiliations of Fiona M. Menzies include University of Sheffield & University of Newcastle.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Regulation of Mammalian Autophagy in Physiology and Pathophysiology

Brinda Ravikumar, +18 more
- 01 Oct 2010 - 
TL;DR: This review focuses on mammalian autophagy, and an overview of the understanding of its machinery and the signaling cascades that regulate it is given, and the possibility of autophagic upregulation as a therapeutic approach for various conditions is considered.
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Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

Fiona M. Menzies, +21 more
- 08 Mar 2017 - 
TL;DR: How autophagy upregulation may be a therapeutic strategy in a wide range of neurodegenerative conditions is described and possible pathways and druggable targets that may be suitable for this objective are considered.
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Lysosomal positioning coordinates cellular nutrient responses

Viktor I. Korolchuk, +12 more
- 01 Apr 2011 - 
TL;DR: It is reported that lysosomal positioning coordinates anabolic and catabolic responses with changes in nutrient availability by orchestrating early plasma-membrane signalling events, mTORC1 signalling and autophagy.
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α-Synuclein impairs macroautophagy: implications for Parkinson’s disease

Ashley R. Winslow, +12 more
- 20 Sep 2010 - 
TL;DR: α-Synuclein impairs autophagosome formation and mislocalizes Atg9 by inhibiting Rab1a.