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Ioannis Mitroulis

Researcher at Democritus University of Thrace

Publications -  99
Citations -  10628

Ioannis Mitroulis is an academic researcher from Democritus University of Thrace. The author has contributed to research in topics: Neutrophil extracellular traps & Haematopoiesis. The author has an hindex of 36, co-authored 82 publications receiving 7681 citations. Previous affiliations of Ioannis Mitroulis include Helmholtz-Zentrum Dresden-Rossendorf & Dresden University of Technology.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity

Ioannis Mitroulis, +30 more
- 11 Jan 2018 - 
TL;DR: The trained-immunity-related increase in myelopoiesis resulted in a beneficial response to secondary LPS challenge and protection from chemotherapy-induced myelosuppression in mice, suggesting modulation of myeloid progenitors in the bone marrow is an integral component of trained immunity.
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Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis.

Panagiotis Skendros, +16 more
- 02 Nov 2020 - 
TL;DR: A mechanistic basis is provided for a pivotal role of complement and NETs in COVID-19 immunothrombosis and supports strategies against SARS-CoV-2 that exploit complement or NETosis inhibition.
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Neutrophil Extracellular Trap Formation Is Associated with IL-1β and Autophagy-Related Signaling in Gout

Ioannis Mitroulis, +8 more
- 16 Dec 2011 - 
TL;DR: These findings document for the first time that activation of neutrophils in gout is associated with the formation of proinflammatory NETs and links this process to both autophagy and IL-1β.
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Expression of functional tissue factor by neutrophil extracellular traps in culprit artery of acute myocardial infarction

Dimitrios Stakos, +10 more
- 07 Jun 2015 - 
TL;DR: Neutrophils are involved in the pathophysiology of infracted coronary arteries in STEMI via NET structures and the blockage of NET formation or local neutralization of NET-mediated TF signalling constitutes candidate therapeutic targets.