Xue-Jun Li

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The results provide compelling evidence that the behavioral effects of curcumin in chronically stressed animals, and by extension humans, may be related to their modulating effects on the HPA axis and neurotrophin factor expressions.

TL;DR: The results suggested that curcumin administration increased hippocampal neurogenesis in chronically stressed rats, similar to classic antidepressant imipramine treatment, and demonstrated that these new cells mature and become neurons, as determined by triple labeling for BrdU and neuronal- or glial-specific markers.

TL;DR: The results confirm the antidepressant effects of curcumin in the forced swim and the OB models of depression in rats, and suggest that these antidepressant effects may be mediated by actions in the central monoaminergic neurotransmitter systems.

TL;DR: The results suggest that the antidepressant-like effects of curcumin may involve the central monoaminergic neurotransmitter systems.