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Vellareddy Anantharam

Researcher at Iowa State University

Publications -  136
Citations -  12418

Vellareddy Anantharam is an academic researcher from Iowa State University. The author has contributed to research in topics: Dopaminergic & Neurodegeneration. The author has an hindex of 53, co-authored 129 publications receiving 10184 citations. Previous affiliations of Vellareddy Anantharam include Johns Hopkins University School of Medicine & University of Massachusetts Amherst.

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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Mitochondria-targeted antioxidants for treatment of Parkinson's disease: preclinical and clinical outcomes.

TL;DR: In this review, the recent developments in mitochondria-targeted antioxidants and their potential beneficial effects as a therapy for ameliorating mitochondrial dysfunction in Parkinson's disease are discussed.
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Caspase-3-Dependent Proteolytic Cleavage of Protein Kinase Cδ Is Essential for Oxidative Stress-Mediated Dopaminergic Cell Death after Exposure to Methylcyclopentadienyl Manganese Tricarbonyl

TL;DR: For the first time, caspase-3-dependent proteolytic activation of PKCδ plays a key role in oxidative stress-mediated apoptosis in dopaminergic cells after exposure to an environmental neurotoxic agent.
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Oxalate:formate exchange. The basis for energy coupling in Oxalobacter.

TL;DR: Assays of reconstitution and heterologous exchange suggested the presence of an unusually rapid and electrogenic oxalate2-:formate1- antiport in membranes of O. formigenes, its immediate metabolic derivative.
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Dieldrin-induced neurotoxicity: relevance to Parkinson's disease pathogenesis.

TL;DR: Various neurotoxic studies conducted in both cell culture and animals models following dieldrin exposure are summarized and discusses their relevance to key pathological mechanisms associated with nigral dopaminergic degeneration including oxidative stress, mitochondrial dysfunction, protein aggregation, and apoptosis.