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Yves L. Marcel

Researcher at University of Ottawa

Publications -  159
Citations -  17288

Yves L. Marcel is an academic researcher from University of Ottawa. The author has contributed to research in topics: Apolipoprotein B & Cholesterol. The author has an hindex of 59, co-authored 159 publications receiving 15940 citations. Previous affiliations of Yves L. Marcel include Wake Forest University & University of California, Los Angeles.

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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol

TL;DR: It is found that rare alleles with major phenotypic effects contribute significantly to low plasma HDL-C levels in the general population.
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High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase

TL;DR: It is shown that HDL stimulates endothelial nitric oxide synthase (eNOS) in cultured endothelial cells through a process that requires ApoA-I binding, and the resulting increase in nitric-oxide production might be critical to the atheroprotective properties of HDL and Apo-I.
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Complete protein sequence and identification of structural domains of human apolipoprotein B

TL;DR: The complete 4,563-amino-acid sequence of apo B-100 precursor (relative molecular mass (Mr) 514,000 (514K)) determined from complementary DNA clones is reported, identifying a domain enriched in basic amino-acid residues as important for the cellular uptake of cholesterol by the LDL receptor pathway.
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Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase

TL;DR: It is concluded that, in macrophage foam cells, lysosomal hydrolysis contributes to the mobilization of LD-associated cholesterol for reverse cholesterol transport.