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Jose Miguel Vicencio

Researcher at University College London

Publications -  52
Citations -  10890

Jose Miguel Vicencio is an academic researcher from University College London. The author has contributed to research in topics: Autophagy & Programmed cell death. The author has an hindex of 33, co-authored 48 publications receiving 9253 citations. Previous affiliations of Jose Miguel Vicencio include Veterinary College, Mathura & Université Paris-Saclay.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Regulation of autophagy by cytoplasmic p53

Ezgi Tasdemir, +40 more
- 04 May 2008 - 
TL;DR: Evidence is provided of a key signalling pathway that links autophagy to the cancer-associated dysregulation of p53, which improved the survival of p 53-deficient cancer cells under conditions of hypoxia and nutrient depletion, allowing them to maintain high ATP levels.
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Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

Roberto Bravo, +20 more
- 01 Jul 2011 - 
TL;DR: It is shown that, during the onset of ER stress, the reticular and mitochondrial networks are redistributed towards the perinuclear area and their points of connection are increased in a microtubule-dependent fashion, which establishes the metabolic basis for the adaptation to this response.
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BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L).

Maria Chiara Maiuri, +7 more
- 11 Apr 2007 - 
TL;DR: A spatial organization of autophagy and apoptosis control in which BH3-only proteins exert two independent functions is suggested, by activating the mitochondrion-permeabilizing function of pro-apoptotic multidomain proteins from the Bcl-2 family.
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Control of autophagy by oncogenes and tumor suppressor genes.

Maria Chiara Maiuri, +16 more
- 01 Jan 2009 - 
TL;DR: The current state-of-the art suggests a complex relationship between cancer and deregulated autophagy that must be disentangled by further in-depth investigation.