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Jianzhen Xu

Researcher at Shantou University

Publications -  55
Citations -  12330

Jianzhen Xu is an academic researcher from Shantou University. The author has contributed to research in topics: microRNA & Gene. The author has an hindex of 25, co-authored 50 publications receiving 10543 citations. Previous affiliations of Jianzhen Xu include Laboratory of Molecular Biology & University of Science and Technology of China.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Discovering disease-genes by topological features in human protein--protein interaction network

TL;DR: This analysis reveals that the hereditary disease-genes ascertained from OMIM in the literature-curated PPIs network are characterized by a larger degree, tendency to interact with other disease- Genes, more common neighbors and quick communication to each other whereas those properties could not be detected from the network identified from high-throughput yeast two-hybrid mapping approach (EXP) and predicted interactions (PDT) PPI network.
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Computational approaches for microRNA studies: a review.

TL;DR: This review briefly outline the biological findings of miRNA genes, such as genomic feature, biogenesis, gene structure, and functional mechanism, and provides perspectives on some emerging issues, including combinatorial regulation by miRNAs and functional binding sites beyond the 3′-untranslated region (3′UTR) of target mRNAs.
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circTADA2As suppress breast cancer progression and metastasis via targeting miR-203a-3p/SOCS3 axis.

TL;DR: They were consistently and significantly decreased in a large cohort of breast cancer patients, and their downregulation was associated with poor patient survival for TNBC, and therapeutic targeting of circTADA2As/miRNA/mRNA network may be a potential strategy for the treatment of Breast cancer.