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Mark E. Drew

Researcher at Ohio State University

Publications -  32
Citations -  6536

Mark E. Drew is an academic researcher from Ohio State University. The author has contributed to research in topics: Kinetoplast & Trypanosoma brucei. The author has an hindex of 23, co-authored 32 publications receiving 5526 citations. Previous affiliations of Mark E. Drew include The Ohio State University Wexner Medical Center & Oregon Health & Science University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Inhibition of Trypanosoma brucei gene expression by RNA interference using an integratable vector with opposing T7 promoters

Zefeng Wang, +3 more
- 22 Dec 2000 - 
TL;DR: A vector for in vivo tetracycline-inducible synthesis of double-stranded RNA (dsRNA) in stably transformed cells is described and one striking phenotype was the loss of kinetoplast DNA after interference with expression of a topoisomerase II.
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The role of plasmodium falciparum food vacuole plasmepsins

Jun Liu, +3 more
- 14 Jan 2005 - 
TL;DR: In this paper, double crossover homologous recombination has been employed to study food vacuole plasmepsin function in cultured P. falciparum and the results suggest substantial functional redundancy and have important implications for the design of antimalarial drugs.
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Glycolysis modulates trypanosome glycoprotein expression as revealed by an RNAi library

James Morris, +3 more
- 02 Sep 2002 - 
TL;DR: The data suggest that T.brucei ‘senses’ changes in glucose level and modulates procyclin expression accordingly, and is supported by observation of a similar upregulation of GPEET‐procyclin when parental cells were grown in medium depleted of glucose.
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Mechanisms of cellular invasion by intracellular parasites.

Dawn M. Walker, +5 more
- 01 Apr 2014 - 
TL;DR: This review is an overview of the molecular mechanisms of protozoan parasite invasion of host cells and discussion of therapeutic strategies, which could be developed by targeting these invasion pathways, which are responsible for significant morbidity and mortality.