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Bryan H. Bellaire

Researcher at Iowa State University

Publications -  55
Citations -  6083

Bryan H. Bellaire is an academic researcher from Iowa State University. The author has contributed to research in topics: Medicine & Antimicrobial. The author has an hindex of 24, co-authored 47 publications receiving 4942 citations. Previous affiliations of Bryan H. Bellaire include Louisiana State University & Iowa State University College of Veterinary Medicine.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Mannose-functionalized "pathogen-like" polyanhydride nanoparticles target C-type lectin receptors on dendritic cells.

TL;DR: A novel approach to targeted antigen delivery is described by decorating the surface of polyanhydride nanoparticles with specific carbohydrates to provide "pathogen-like" properties that ensure nanoparticles engage C-type lectin receptors on DCs.
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Polyanhydride microparticles enhance dendritic cell antigen presentation and activation.

TL;DR: Data indicate that polyanhydride particles can be tailored to take advantage of the potential plasticity of the immune response, resulting in the ability to induce immune protection against many types of pathogens.
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Adaptation of the Brucellae to their intracellular niche.

TL;DR: Experimental evidence suggests that these bacteria use an iron acquisition system to support extensive intracellular replication within these host cells that is not required for survival and replication in host macrophages.
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Polymer chemistry influences monocytic uptake of polyanhydride nanospheres.

TL;DR: Nanosphere and antigen uptake by monocytes can be directly correlated to the chemistry of the nanosphere and the importance of choosing polyanhydride chemistries that facilitate enhanced interactions with antigen presenting cells that are necessary in the initiation of efficacious immune responses is demonstrated.