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Shi-Yong Sun

Researcher at Emory University

Publications -  224
Citations -  21621

Shi-Yong Sun is an academic researcher from Emory University. The author has contributed to research in topics: Apoptosis & Cancer. The author has an hindex of 64, co-authored 205 publications receiving 19137 citations. Previous affiliations of Shi-Yong Sun include Emory Healthcare & University of Texas MD Anderson Cancer Center.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.

TL;DR: This study provides a mechanistic basis for enhancing mTOR-targeted cancer therapy by combining an mTOR inhibitor with a PI3K or Akt inhibitor and shows that rapamycin combined with LY294002 exhibited enhanced inhibitory effects on the growth and colony formation of cancer cells.
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Apoptosis as a novel target for cancer chemoprevention

TL;DR: A paradigm supporting apoptosis as a novel target for cancerChemoprevention is constructed by highlighting recent studies of several chemopreventive agents that engage apoptosis pathways.
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Retinoids and their receptors in cancer development and chemoprevention.

TL;DR: Vitamin A deficiency in experimental animals has been associated with a higher incidence of cancer and with increased susceptibility to chemical carcinogens, in agreement with the epidemiological studies indicating that individuals with a lower dietary vitamin A intake are at a higher risk to develop cancer.