Mantong Zhao

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The concept and physiological function of autophagy, and the proteins related to autosomal dominant and autosomal recessive PD, particularly α-synuclein and PINK1-PARKIN, as they pertain to autophileagy are introduced.

TL;DR: The MAP kinase Slt2 is required for both mitophagy and pexophagy, whereas the MAP kinases Hog1 and Hog1 acts specifically inMitophagy.

TL;DR: This study identifies ULK1 as a substrate for AMPK phosphorylation, a modification required for selective autophagy of mitochondria and cell survival during starvation.

TL;DR: Data reveal a key role for PtdIns3P turnover in the regulation of the late steps of autophagosome biogenesis and indicate that the disassembly of the Atg machinery from the surface of Autophagosomes is a requisite for their fusion with the vacuole.