Michael Lehmann

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: It is shown that the single lipin orthologue of Drosophila melanogaster (dLipin) is essential for normal adipose tissue (fat body) development and TAG storage and under starvation conditions, dLipin is transcriptionally upregulated and functions to promote survival.

TL;DR: Recent insights into the composition and architecture of GAGA-binding protein complexes are summarized, and their multifaceted role in homeotic gene regulation is discussed.

TL;DR: A complete colocalization of Psq and GAF on polytene interphase chromosomes and mitotic chromosomes suggests that the two proteins cooperate as general partners not only at homeotic loci, but also at hundreds of other chromosomal sites.

TL;DR: It is found that loss of the tissue-specific transcription factor Fork head (Fkh) is both required and sufficient to specify a death response to 20E in the larval salivary glands, suggesting that cell identity factors like Fkh play a pivotal role in the normal control of developmental cell death.