Mette Prætorius-Ibba

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Evidence is provided that Cullin 4A (CUL-4A) mediates the proteolytic degradation of DDB2 and that this degradation event, initiated at the lesion sites, regulates damage recognition by XPC during the early steps of NER.

TL;DR: It is shown that Microcin C is a subject of specific degradation inside the sensitive cell, and the product of degradation strongly inhibits translation by blocking the function of aspartyl-tRNA synthetase.

TL;DR: It is shown that DDB1 knockdown in human cells impaired their ability to efficiently repair UV-induced cyclobutane pyrimidine dimers (CPD) but not 6-4 photoproducts (6-4PP).

TL;DR: Evidence is provided for the involvement of UPS in the transcriptional activation function of tumor suppressor p53 and it is suggested that UPS positively regulates p53-mediated transcription at p21waf1 promoter.