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Simon R. Carding

Researcher at University of East Anglia

Publications -  222
Citations -  18336

Simon R. Carding is an academic researcher from University of East Anglia. The author has contributed to research in topics: T cell & Cytotoxic T cell. The author has an hindex of 55, co-authored 205 publications receiving 15096 citations. Previous affiliations of Simon R. Carding include Quadram Institute & Howard Hughes Medical Institute.

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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Inflammatory bowel disease: cause and immunobiology

TL;DR: How environmental factors, infectious microbes, ethnic origin, genetic susceptibility, and a dysregulated immune system can result in mucosal inflammation are discussed.
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Dysbiosis of the gut microbiota in disease

TL;DR: Data suggest that CNS-related co-morbidities frequently associated with GI disease may originate in the intestine as a result of microbial dysbiosis, and the potential to positively modulate the composition of the colonic microbiota and ameliorate disease activity through bacterial intervention.
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Gammadelta T cells: functional plasticity and heterogeneity.

TL;DR: It is argued that γδ T cells perform different functions according to their tissue distribution, antigen-receptor structure and local microenvironment, and how and at what stage of the immune response they become activated.
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Roles of alpha beta and gamma delta T cell subsets in viral immunity.

TL;DR: It is made that alpha beta T-cell memory to viruses is long-lived, and the need for antigen persistence to maintain such memory is questioned, and there is as yet no understanding of the biological significance (if any) of these lymphocytes in viral immunity.