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Massimo De Felici

Researcher at University of Rome Tor Vergata

Publications -  142
Citations -  9253

Massimo De Felici is an academic researcher from University of Rome Tor Vergata. The author has contributed to research in topics: Germ cell & Somatic cell. The author has an hindex of 37, co-authored 128 publications receiving 7689 citations. Previous affiliations of Massimo De Felici include University of Pennsylvania & Sapienza University of Rome.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death.

Stefania Gonfloni, +11 more
- 27 Sep 2009 - 
TL;DR: Data support a model in which signals initiated by DNA double-strand breaks are detected by c-Abl, which, through its kinase activity, modulates the p63 transcriptional output, and suggest a new use for imatinib, aimed at preserving oocytes of the follicle reserve during chemotherapeutic treatments.
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Spontaneous hardening of the zona pellucida of mouse oocytes during in vitro culture

Massimo De Felici, +1 more
- 01 Jan 1982 - 
TL;DR: The results suggest that the “spontaneous” hardening in cultured ovarian oocytes is not due to a cortical reaction, and that a diffusible factor is produced by follicle cells that protect the ZP from hardening.
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Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells

Florencia Barrios, +9 more
- 15 Mar 2010 - 
TL;DR: It is shown that Nanos2 is continuously expressed in male germ cells from fetal gonocytes to postnatal spermatogonial stem cells and that NANOS2 interacts with PUM2, and that these two proteins colocalize in the ribonucleoparticle and polysomal fractions on sucrose gradients, supporting the notion that they bind RNA.
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Down-regulation of anandamide hydrolase in mouse uterus by sex hormones

Mauro Maccarrone, +5 more
- 01 May 2000 - 
TL;DR: Evidence of an interplay between endocannabinoids and sex hormones in pregnancy is provided and may be relevant for human fertility, as epithelial cells from healthy human uterus showed FAAH activity and expression, which in adenocarcinoma cells was increased fivefold.