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Raj Kumar

Researcher at The Commonwealth Medical College

Publications -  62
Citations -  7084

Raj Kumar is an academic researcher from The Commonwealth Medical College. The author has contributed to research in topics: Glucocorticoid receptor & Protein structure. The author has an hindex of 28, co-authored 58 publications receiving 5897 citations. Previous affiliations of Raj Kumar include University of Texas Medical Branch.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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The Dynamic Structure of the Estrogen Receptor

Raj Kumar, +8 more
- 26 Jul 2011 - 
TL;DR: The knowledge about the structural characteristics of the ER in general and how the structural features of the two isoforms differ, and its subsequent role in gene regulation are discussed.
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Trimethylamine N-Oxide-induced Cooperative Folding of an Intrinsically Unfolded Transcription-activating Fragment of Human Glucocorticoid Receptor

Ilia V. Baskakov, +5 more
- 16 Apr 1999 - 
TL;DR: CD and fluorescence spectroscopy demonstrated that the TMAO-induced structure is different from the α-helix-rich conformation driven by trifluoroethanol (TFE), and the conformational transition of the 1–500 fragment induced by T MAO is cooperative, a condition characteristic of proteins with unique structures.
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The conformation of the glucocorticoid receptor af1/tau1 domain induced by osmolyte binds co-regulatory proteins.

Raj Kumar, +3 more
- 25 May 2001 - 
TL;DR: It is shown that in buffers containing the natural osmolyte trimethylamineN-oxide (TMAO), recombinant AF1 folds into more a compact structure, as evidenced by altered fluorescence emission, circular dichroism spectra, and ultracentrifugal analysis.
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Role of naturally occurring osmolytes in protein folding and stability.

Raj Kumar
- 01 Nov 2009 - 
TL;DR: Proper understanding of the role of osmolytes in cell regulation should allow predicting the action of o smolytes on macromolecular interactions in stressed and crowded environments typical of cellular conditions.