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Jian Feng

Researcher at University at Buffalo

Publications -  146
Citations -  20031

Jian Feng is an academic researcher from University at Buffalo. The author has contributed to research in topics: Parkin & Induced pluripotent stem cell. The author has an hindex of 68, co-authored 135 publications receiving 17695 citations. Previous affiliations of Jian Feng include St. Jude Children's Research Hospital & Capital Medical University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons

Jian Feng, +8 more
- 01 Apr 2010 - 
TL;DR: Dnmt1 and Dnmt3a are required for synaptic plasticity, learning and memory through their overlapping roles in maintaining DNA methylation and modulating neuronal gene expression in adult CNS neurons.
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Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens

Quincey LaPlant, +30 more
- 01 Sep 2010 - 
TL;DR: The found that chronic cocaine use selectively increased thin dendritic spines on NAc neurons and that DNA methylation was both necessary and sufficient to mediate these effects, establish the importance of Dnmt3a in the NAc in regulating cellular and behavioral plasticity to emotional stimuli.
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Phospholipase Cγ2 Is Essential in the Functions of B Cell and Several Fc Receptors

Demin Wang, +13 more
- 01 Jul 2000 - 
TL;DR: A signal transduction pathway broadly utilized by immunoglobulin superfamily receptors is defined, with similarity to Btk- or Blnk-deficient mice demonstrates that PLCgamma2 is downstream in Btk/Blnk signaling.
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Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson’s Disease

Oliver Cooper, +39 more
- 04 Jul 2012 - 
TL;DR: Analysis of mitochondrial responses in iPSC-derived neural cells from PD patients carrying different mutations provides insight into convergence of cellular disease mechanisms between different familial forms of PD and highlights the importance of oxidative stress and mitochondrial dysfunction in this neurodegenerative disease.