Giampietro Viola

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Flow cytometry studies showed that HeLa and Jurkat cells treated with the most active compounds 4l and 4o were arrested in the G2/M phase of the cell cycle in a concentration dependent manner, accompanied by apoptosis of the cells, mitochondrial depolarization, generation of reactive oxygen species, activation of caspase-3, and PARP cleavage.

TL;DR: The major advances in the study of GSC role in GBM and the therapeutic implications resulting from them are discussed, thus reporting the latest strategies applied to counteract and overcome GBM intrinsic resistance to therapy for a better management of patients.

TL;DR: The absorption and steady-state emission properties of a series of N-alkyl- and N-aryl-9-aminoacridizinium derivatives and two 9-sulfanyl-substituted acridiz inium derivatives were investigated and it was demonstrated that the excited-state deactivation of the H2O derivatives is due to two nonradiative processes.