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Chengyu Liang

Researcher at University of Southern California

Publications -  72
Citations -  17018

Chengyu Liang is an academic researcher from University of Southern California. The author has contributed to research in topics: Autophagy & UVRAG. The author has an hindex of 35, co-authored 70 publications receiving 14858 citations. Previous affiliations of Chengyu Liang include Stony Brook University & Harvard University.

Papers
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

Michaela U. Gack, +13 more
- 19 Apr 2007 - 
TL;DR: It is demonstrated that TRIM25 E3 ubiquitin ligase induces the Lys 63-linked ubiquitination of RIG-I, which is crucial for the cytosolic Rig-I signalling pathway to elicit host antiviral innate immunity.
Journal ArticleDOI

Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

Chengyu Liang, +6 more
- 25 Jun 2006 - 
TL;DR: UVRAG is identified as an essential component of the Beclin1–PI(3)KC3 lipid kinase complex that is an important signalling checkpoint for autophagy and tumour-cell growth.
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Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis.

Yoshinori Takahashi, +11 more
- 23 Sep 2007 - 
TL;DR: It is demonstrated that Bif-1 interacts with Beclin 1 through ultraviolet irradiation resistance-associated gene (UVRAG) and functions as a positive mediator of the class III PI(3) kinase (PI( 3)KC3) and observed that B if-1 ablation prolongs cell survival under starvation conditions.