scispace - formally typeset
C

Chenguang Wang

Researcher at Johns Hopkins University

Publications -  241
Citations -  20875

Chenguang Wang is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Cyclin D1 & Cyclin D. The author has an hindex of 63, co-authored 211 publications receiving 18379 citations. Previous affiliations of Chenguang Wang include Nankai University & University of Washington.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

Stephanos Pavlides, +13 more
- 01 Dec 2009 - 
TL;DR: In this alternative model of tumorigenesis, the epithelial cancer cells instruct the normal stroma to transform into a wound-healing stroma, providing the necessary energy-rich micro-environment for facilitating tumor growth and angiogenesis, explaining its powerful predictive value.
Journal ArticleDOI

Minireview: Cyclin D1: normal and abnormal functions.

Maofu Fu, +4 more
- 01 Dec 2004 - 
TL;DR: Accumulating evidence suggests that in addition to its original description as a CDK-dependent regulator of the cell cycle, cyclin D1 also conveys cell cycle orCDK-independent functions.
Journal ArticleDOI

Improved Early Event-Free Survival With Imatinib in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: A Children's Oncology Group Study

Kirk R. Schultz, +19 more
- 01 Nov 2009 - 
TL;DR: The higher imatinib dosing in cohort 5 appears to improve survival by having an impact on the outcome of children with a higher burden of minimal residual disease after induction, with no appreciable increase in toxicity.
Journal ArticleDOI

Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells

Ubaldo E. Martinez-Outschoorn, +17 more
- 15 Aug 2010 - 
TL;DR: Cancer cells use "oxidative stress" in adjacent fibroblasts as an "engine" to fuel their own survival via the stromal production of nutrients, and to drive their own mutagenic evolution towards a more aggressive phenotype, by promoting genomic instability.