Mehrdad Alirezaei

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The method is used to identify constitutive autophagosomes in cortical neurons and Purkinje cells, and it is shown that short-term fasting leads to a dramatic up-regulation in neuronal autophagy, which is speculated to represent a simple, safe and inexpensive means to promote this potentially-therapeutic neuronal response.

TL;DR: In vivo studies demonstrate that CVB3 infection dramatically modifies autophagy in infected pancreatic acinar cells, and indicates that this pathway may represent a coxsackievirus replication complex.

TL;DR: Results identify that induction of deficits in autophagy is a significant mechanism for neurodegenerative processes that arise from glial, as opposed to neuronal, sources, and that the maintenance of autophagic activity may have a pivotal role in neuroprotection in the setting of HIV infection.