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Frederic Luciano

Researcher at French Institute of Health and Medical Research

Publications -  77
Citations -  14531

Frederic Luciano is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Apoptosis & Programmed cell death. The author has an hindex of 34, co-authored 75 publications receiving 12692 citations. Previous affiliations of Frederic Luciano include University of Nice Sophia Antipolis & Sanford-Burnham Institute for Medical Research.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation.

Benjamin Faustin, +9 more
- 09 Mar 2007 - 
TL;DR: The findings provide the biochemical basis for understanding how inflammasome assembly and function are regulated, and shed light on NALP1 as a direct sensor of bacterial components in host defense against pathogens.
Journal ArticleDOI

Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

Frederic Luciano, +6 more
- 02 Oct 2003 - 
TL;DR: It is reported here that Bim-EL when phosphorylated by Erk1/2 is rapidly degraded via the proteasome pathway, and therefore represents a new and important mechanism of Bim regulation.
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Resveratrol Promotes Autophagic Cell Death in Chronic Myelogenous Leukemia Cells via JNK-Mediated p62/SQSTM1 Expression and AMPK Activation

Alexandre Puissant, +6 more
- 01 Feb 2010 - 
TL;DR: It is concluded that RSV triggered autophagic cell death in CML cells via both JNK-mediated p62 overexpression and AM PK activation, and the findings show that the JNK and AMPK pathways can cooperate to eliminate C ML cells via autophagy.