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Lin Zhang

Researcher at Sun Yat-sen University

Publications -  396
Citations -  29665

Lin Zhang is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Apoptosis & Cancer. The author has an hindex of 66, co-authored 347 publications receiving 26295 citations. Previous affiliations of Lin Zhang include Howard Hughes Medical Institute & University of Pittsburgh.

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Serial analysis of gene expression

TL;DR: Serial analysis of gene expression (SAGE) should provide a broadly applicable means for the quantitative cataloging and comparison of expressed genes in a variety of normal, developmental, and disease states.
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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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PUMA induces the rapid apoptosis of colorectal cancer cells.

TL;DR: Through global profiling of genes that were expressed soon after p53 expression, a novel gene termed PUMA (p53 upregulated modulator of apoptosis) was identified and it was found to be exclusively mitochondrial and to bind to Bcl-2 and Bcl(L) through a BH3 domain.
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14-3-3σ Is a p53-Regulated Inhibitor of G2/M Progression

TL;DR: It is discovered that 14-3-3σ is strongly induced by γ irradiation and other DNA-damaging agents, and mediated by a p53-responsive element located 1.8 kb upstream of its transcription start site.
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Whole genome amplification from a single cell: implications for genetic analysis

TL;DR: W Whole genome amplification beginning with a single cell, or other samples with very small amounts of DNA, has significant implications for multipoint mapping by sperm or oocyte typing and possibly for genetic disease diagnosis, forensics, and the analysis of ancient DNA samples.