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James M. Phang

Researcher at National Institutes of Health

Publications -  129
Citations -  18041

James M. Phang is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Proline & Proline oxidase. The author has an hindex of 52, co-authored 128 publications receiving 16135 citations.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Molecular effects of genistein on estrogen receptor mediated pathways

TL;DR: Genistein, though estrogenic, can interfere with the effects of estradiol and prolonged exposure to genistein resulted in a decrease in estrogen receptor mRNA level as well as a decreased response to stimulation byEstradiol.
Journal ArticleDOI

Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC.

TL;DR: Using MYC-inducible human Burkitt lymphoma model P493 and PC3 human prostate cancer cells, it is shown that MYC suppressed POX/PRODH expression primarily through up-regulating miR-23b*.
Journal ArticleDOI

Depletion of Intracellular Ascorbate by the Carcinogenic Metals Nickel and Cobalt Results in the Induction of Hypoxic Stress

TL;DR: It is suggested that the observed depletion of ascorbate by nickel( II) or cobalt(II) favors iron oxidation and thus inactivation of the enzyme, which is essential for maintaining iron in prolyl hydroxylases in the active iron(II] state.