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James B. Hurley

Researcher at University of Washington

Publications -  181
Citations -  18125

James B. Hurley is an academic researcher from University of Washington. The author has contributed to research in topics: Transducin & Rhodopsin. The author has an hindex of 63, co-authored 173 publications receiving 16300 citations. Previous affiliations of James B. Hurley include University of Washington Medical Center & Moscow State University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Flow of information in the light-triggered cyclic nucleotide cascade of vision.

Bernard K.-K. Fung, +2 more
- 01 Jan 1981 - 
TL;DR: It is found that phosphodiesterase on unilluminated disc membranes can indeed be fully activated by addition of T alpha containing bound p[NH]ppG, suggesting that transducin is the first amplified information-carrying intermediate in the cyclic nucleotide cascade of vision.
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Distribution and morphology of human cone photoreceptors stained with anti-blue opsin.

Christine A. Curcio, +6 more
- 22 Oct 1991 - 
TL;DR: Primate cones maximally sensitive to short wavelength light (blue cones) have been previously identified by using indirect methods and stained wholemounted human retinas obtained from 6 female donors using an affinity purified antibody to a 19 amino acid peptide sequence at the N‐terminus of blue opsin.
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Recoverin: a calcium sensitive activator of retinal rod guanylate cyclase.

Alexander M. Dizhoor, +9 more
- 22 Feb 1991 - 
TL;DR: Vertebrate retinal photoreceptors recover from photoexcitation-induced hydrolysis of guanosine 3', 5'-monophosphate (cyclic GMP) by resynthesizing cyclicGMP, which reopens cation channels that have been closed by light.
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A thyroid hormone receptor that is required for the development of green cone photoreceptors.

Lily Ng, +7 more
- 01 Jan 2001 - 
TL;DR: The results indicate that cone photoreceptors throughout the retina have the potential to follow a default S-cone pathway and reveal an essential role for Trβ2 in the commitment to an M-cone identity, and raise the possibility that Thrb mutations may be associated with human cone disorders.