Ke Wang

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: It is found that YIL146C/ECM37 is essential for mitophagy and this autophagy-related (ATG) gene is designated as ATG32, and the Atg32 protein localizes on mitochondria and confers selectivity for mitochondrial sequestration as a cargo.

TL;DR: Evidence is provided for the involvement of exocytic Q/t-SNAREs in autophagosome formation, acting in the recruitment of key autophagy components to the site of autophagic formation, and in regulating the organization of Atg9 into tubulovesicular clusters.

TL;DR: This review compares the molecular process of mitophagy with other types of specific autophagic pathways and discusses its biological importance.

TL;DR: The concept and physiological function of autophagy, and the proteins related to autosomal dominant and autosomal recessive PD, particularly α-synuclein and PINK1-PARKIN, as they pertain to autophileagy are introduced.