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Jean-Claude Farré

Researcher at University of California, San Diego

Publications -  39
Citations -  6600

Jean-Claude Farré is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Autophagy & Peroxisome. The author has an hindex of 23, co-authored 38 publications receiving 5451 citations. Previous affiliations of Jean-Claude Farré include Centre national de la recherche scientifique & University of Bordeaux.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Mechanistic insights into selective autophagy pathways: lessons from yeast

TL;DR: Yeast studies have provided novel mechanistic insights into selective autophagy pathways, revealing principles of how various cargoes can be marked and targeted for selective degradation.
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PpAtg30 tags peroxisomes for turnover by selective autophagy.

TL;DR: PpAtg30 is a key player in the selection of peroxisomes as cargo and in their delivery to the autophagy machinery for pexophagy, and is required for formation of pexophile intermediates, such as the micropexophagy apparatus (MIPA) and the peXophagosome (Ppg).
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Peroxisome turnover by micropexophagy: an autophagy-related process

TL;DR: Advances in the characterization of genes that are necessary for the transport and delivery of selective and nonselective cargoes to the lysosome or vacuole by autophagy-related processes are summarized, with emphasis on peroxisome turnover by micropexophagy.
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Phosphorylation of mitophagy and pexophagy receptors coordinates their interaction with Atg8 and Atg11.

TL;DR: A common model for the phosphoregulation of selective autophagy receptors is presented and it is confirmed that the Pichia pastoris pexophagy receptor, Atg30, also interacts with Atg8.