Jenny Campos-Salinas

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The vasoactive intestinal peptide is used as an example of an immunomodulatory neuropeptide to summarize the most relevant data found for other neuropepeptides with similar characteristics, including adrenomedullin, urocortin, cortistatin and ghrelin.

TL;DR: Biophysical experiments showed that EBR1, a 29 nucleotide long highly repeated PQS in T. brucei, forms a stable G4 structure and G4 ligands based on carbohydrate conjugated naphthalene diimides that bind G4’s including hTel could bind E BR1 with selectivity versus dsDNA, which showed important antiparasitic activity.

TL;DR: How distinct cell death pathways in Trypanosoma, Leishmania, Plasmodium or Toxoplasma may contribute to regulation of parasite cell densities in vectors and mammalian hosts, to differentiation of parasites, to stress responses, and to modulation of the host immunity is reviewed.

TL;DR: Interestingly, when monosaccharides were attached through a short ethylene linker to the NDI scaffold, their cellular uptake was two- to threefold more efficient than that when the sugar was directly attached through its anomeric position.