scispace - formally typeset
P

Philippe Marambaud

Researcher at The Feinstein Institute for Medical Research

Publications -  105
Citations -  17431

Philippe Marambaud is an academic researcher from The Feinstein Institute for Medical Research. The author has contributed to research in topics: CALHM1 & Presenilin. The author has an hindex of 40, co-authored 98 publications receiving 15425 citations. Previous affiliations of Philippe Marambaud include Icahn School of Medicine at Mount Sinai & Centre national de la recherche scientifique.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Resveratrol Promotes Clearance of Alzheimer's Disease Amyloid-β Peptides

Philippe Marambaud, +2 more
- 11 Nov 2005 - 
TL;DR: A proteasome-dependent anti-amyloidogenic activity of resveratrol is demonstrated and it is suggested that this natural compound has a therapeutic potential in Alzheimer's disease.
Journal ArticleDOI

A presenilin‐1/γ‐secretase cleavage releases the E‐cadherin intracellular domain and regulates disassembly of adherens junctions

Philippe Marambaud, +11 more
- 15 Apr 2002 - 
TL;DR: It is shown that presenilin‐1 (PS1), a protein involved in Alzheimer's disease, controls a γ‐secretase‐like cleavage of E‐cadherin that stimulates disassembly of the E‐ cadher in– catenin complex and increases the cytosolic pool of β‐catenin, a key regulator of the Wnt signaling pathway.
Journal ArticleDOI

AMP-activated Protein Kinase Signaling Activation by Resveratrol Modulates Amyloid-β Peptide Metabolism

Valérie Vingtdeux, +12 more
- 19 Mar 2010 - 
TL;DR: It is shown that AMPK signaling controls Aβ metabolism and mediates the anti-amyloidogenic effect of resveratrol in non-neuronal and neuronal cells, including in mouse primary neurons, and that resver atrol and pharmacological activation of AMPK have therapeutic potential against Alzheimer disease.