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Qi-Wen Fan

Researcher at University of California, San Francisco

Publications -  56
Citations -  9881

Qi-Wen Fan is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: PI3K/AKT/mTOR pathway & Protein kinase B. The author has an hindex of 35, co-authored 56 publications receiving 8462 citations. Previous affiliations of Qi-Wen Fan include Genentech & University of California.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

Qi-Wen Fan, +7 more
- 01 May 2006 - 
TL;DR: Surprisingly, a single agent (PI-103) effected proliferative arrest in glioma cells, despite the ability of many compounds to block PI3 kinase signaling through its downstream effector, Akt.
Journal ArticleDOI

Epidermal growth factor receptor and EGFRvIII in glioblastoma: signaling pathways and targeted therapies.

Z. H. An, +4 more
- 11 Jan 2018 - 
TL;DR: Signaling pathways mediated by EGFR/EGFRvIII, current therapeutics, and novel strategies to target EGFR-tyrosine kinase inhibitors (TKIs) or antibodies are discussed.
Journal ArticleDOI

Akt and Autophagy Cooperate to Promote Survival of Drug-Resistant Glioma

Qi-Wen Fan, +11 more
- 09 Nov 2010 - 
TL;DR: The dual PI3K-mTOR inhibitor PI-103 induces autophagy in a form of glioma that is resistant to therapy, and elicited cell death with combinations of drugs that are either now in use in patients or in clinical trials, raising the hope that this approach could be readily translatable to human therapy.
Journal ArticleDOI

A Null Mutation in Basigin, an Immunoglobulin Superfamily Member, Indicates Its Important Roles in Peri-implantation Development and Spermatogenesis

Tadahiko Igakura, +15 more
- 15 Feb 1998 - 
TL;DR: It is suggested that basigin is involved in intercellular recognition during implantation, and an important cell-surface molecule involved in early embryogenesis and reproduction.