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Katsuhiko Asanuma

Researcher at Chiba University

Publications -  97
Citations -  12822

Katsuhiko Asanuma is an academic researcher from Chiba University. The author has contributed to research in topics: Podocyte & Slit diaphragm. The author has an hindex of 26, co-authored 86 publications receiving 11078 citations. Previous affiliations of Katsuhiko Asanuma include Niigata University & Juntendo University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton

TL;DR: The fact that the dynamic regulation of the podocyte cytoskeleton is vital to kidney function has led to podocytes emerging as an excellent model system for studying actin cytos skeleton dynamics in a physiological context.
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Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signalling

TL;DR: Gene silencing of synaptopodin in kidney podocytes causes the loss of stress fibres and the formation of aberrant non-polarized filopodia and impairment of cell migration, and shows that syn laptopodin is essential for the integrity of the podocyte actin cytoskeleton and for the regulation of podocyte cell migration.
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Impaired Podocyte Autophagy Exacerbates Proteinuria in Diabetic Nephropathy.

TL;DR: It is suggested that autophagy plays a pivotal role in maintaining lysosome homeostasis in podocytes under diabetic conditions, and that its impairment is involved in the pathogenesis of podocyte loss, leading to massive proteinuria in diabetic nephropathy.