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J. Wade Harper

Researcher at Harvard University

Publications -  292
Citations -  75309

J. Wade Harper is an academic researcher from Harvard University. The author has contributed to research in topics: Ubiquitin ligase & Ubiquitin. The author has an hindex of 109, co-authored 279 publications receiving 66267 citations. Previous affiliations of J. Wade Harper include University of Wisconsin-Madison & Institute of Cancer Research.

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

J. Wade Harper, +4 more
- 19 Nov 1993 - 
TL;DR: In this article, an improved two-hybrid system was employed to isolate human genes encoding Cdk-interacting proteins (Cips) and found that CIP1 is a potent, tight-binding inhibitor of Cdks and can inhibit the phosphorylation of Rb by cyclin A-Cdk2.
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

Chu-Xia Deng, +7 more
- 25 Aug 1995 - 
TL;DR: The results establish the role of p21CIP1/WAF1 in the G1 checkpoint, but suggest that the anti-apoptotic and theAnti-oncogenic effects of p53 are more complex.
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A Map of the Interactome Network of the Metazoan C. elegans

Siming Li, +50 more
- 23 Jan 2004 - 
TL;DR: A large fraction of the Caenorhabditis elegans interactome network is mapped, starting with a subset of metazoan-specific proteins, and more than 4000 interactions were identified from high-throughput, yeast two-hybrid screens.