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Saverio Minucci

Researcher at European Institute of Oncology

Publications -  237
Citations -  33456

Saverio Minucci is an academic researcher from European Institute of Oncology. The author has contributed to research in topics: Histone deacetylase & Promyelocytic leukemia protein. The author has an hindex of 67, co-authored 220 publications receiving 30406 citations. Previous affiliations of Saverio Minucci include Sapienza University of Rome & National Institutes of Health.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

TL;DR: Investigating aspects of HDACi action both in vitro and in vivo will further improve the design of optimized clinical protocols and help to understand the role of histone deacetylases in tumorigenesis.
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Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

TL;DR: Valproic acid induces differentiation of carcinoma cells, transformed hematopoietic progenitor cells and leukemic blasts from acute myeloid leukemia patients, and tumor growth and metastasis formation are significantly reduced in animal experiments, suggesting that it might serve as an effective drug for cancer therapy.
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The tripartite motif family identifies cell compartments.

TL;DR: The results demonstrate that TRIM proteins share a common function: by means of homo‐multimerization they identify specific cell compartments.