Tapas Saha

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Oxidative stress and estrogen receptor-associated proliferative changes are suggested to play important roles in estrogen-induced breast carcinogenesis and BRCA1, a tumor suppressor against hormone responsive cancers such as breast and prostate cancer, plays a significant role in inhibiting ROS and estrogen mediated DNA damage.

TL;DR: This Connections Map Pathway in the Database of Cell Signaling integrates signaling not only from TGF-β and BMP but also from the ligands nodal and activin, and describes the role of the signaling pathways activated by these ligands in mammalian development.

TL;DR: This review is focused on the patents generated on the effects of I3C, DIM and selected phytochemicals of cardamom on carcinogenesis.

TL;DR: It is found that BRCA1 regulates the length of the 3′ G-rich overhang in a manner that is dependent upon Rad50, and the findings suggest that B RCA1 is recruited to the telomere in a Rad50-dependent manner and that BrcA1 may regulate telomeres length and stability, in part through its presence at thetelomere.